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Mark Duxbury 2019 | Consultant Hepatobiliary, Pancreatic & General Surgeon | Glasgow

 

MARK DUXBURY

Publications

Selected peer reviewed publications

 

Robertson N, Gallacher PJ, Peel N, Garden OJ, Duxbury MS, Lassen K, et al. Implementation of an enhanced recovery programme following pancreaticoduodenectomy. HPB (Oxford). 2012 Oct;14(10):700-8.
 

Harrison EM, O'Neill S, Meurs TS, Wong PL, Duxbury MS, Paterson-Brown S, et al. Hospital volume and patient outcomes after cholecystectomy in Scotland: retrospective, national population based study. Bmj. 2012;344:e3330.
 

Elhassan MO, Christie J, Duxbury MS. Homo sapiens systemic RNA interference defective-1 transmembrane family member 1 (SIDT1) mediates contact-dependent small RNA transfer and microRNA-21-driven chemoresistance. J Biol Chem. 2011 Dec 15.
 

Duxbury MS. CEACAM1 cytoplastic expression is closely related to tumor angiogenesis and poorer relapse-free survival after curative resection of hepatocellular carcinoma. World J Surg. 2011 Oct;35(10):2266-7.
 

Velu PP, Hor K, Leighton S, Yeoh SE, Duxbury MS. Cost-utility and value-of-information analysis of early versus delayed laparoscopic cholecystectomy for acute cholecystitis (Br J Surg 2010; 97: 210-219). Br J Surg. 2010 Jul;97(7):1149-50; author reply 50-1.
 

Duxbury MS, Garden OJ. Giant haemangioma of the liver: observation or resection? Dig Surg. 2010;27(1):7-11.
 

Lidder PG, Lewis S, Duxbury MS, Thomas S. Systematic review of postdischarge oral nutritional supplementation in patients undergoing GI surgery. Nutr Clin Pract. 2009 Jun-Jul;24(3):388-94.
 

Smith SL, Hampson F, Duxbury MS, Rae DM, Sinclair MT. Computed tomography after radical pancreaticoduodenectomy (Whipple's procedure). Clin Radiol. 2008 Aug;63(8):921-8.
 

Waseem T, Duxbury MS, Ito H, Ashley SW, Robinson MK. Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways. Surgery. 2008 Mar;143(3):334-42.
 

Duxbury MS, Whang EE. RRM2 induces NF-kappaB-dependent MMP-9 activation and enhances cellular invasiveness. Biochem Biophys Res Commun. 2007 Mar 2;354(1):190-6.
 

Duxbury MS, Keeling N. Cost-effective laparoscopic appendicectomy. Surg Endosc. 2006 Mar;20(3):535.
 

Duxbury MS, Ito H, Benoit E, Waseem T, Ashley SW, Whang EE. RNA interference demonstrates a novel role for integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell gemcitabine chemoresistance. Clin Cancer Res. 2005 May 1;11(9):3433-8.
 

Duxbury MS, Ashley SW, Whang EE. RNA interference: a mammalian SID-1 homologue enhances siRNA uptake and gene silencing efficacy in human cells. Biochem Biophys Res Commun. 2005 Jun 3;331(2):459-63.
 

Perez A, Duxbury MS, Rocha FG, Ramsanahie AP, Farivar RS, Varnholt H, et al. Glucagon-like peptide 2 is an endogenous mediator of postresection intestinal adaptation. JPEN J Parenter Enteral Nutr. 2005 Mar-Apr;29(2):97-101.
 

Duxbury MS, Matros E, Clancy T, Bailey G, Doff M, Zinner MJ, et al. CEACAM6 is a novel biomarker in pancreatic adenocarcinoma and PanIN lesions. Ann Surg. 2005 Mar;241(3):491-6.
 

Ito H, Duxbury MS, Benoit E, Clancy TE, Zinner MJ, Ashley SW, et al. Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2. Cancer Res. 2004 Oct 15;64(20):7439-46.
 

Duxbury MS, Matros E, Ito H, Zinner MJ, Ashley SW, Whang EE. Systemic siRNA-mediated gene silencing: a new approach to targeted therapy of cancer. Ann Surg. 2004 Oct;240(4):667-74; discussion 75-6.
 

Ito H, Duxbury MS, Zinner MJ, Ashley SW, Whang EE. Glucose transporter-1 gene expression is associated with pancreatic cancer invasiveness and MMP-2 activity. Surgery. 2004 Sep;136(3):548-56.
 

Duxbury MS, Ito H, Benoit E, Ashley SW, Whang EE. CEACAM6 is a determinant of pancreatic adenocarcinoma cellular invasiveness. Br J Cancer. 2004 Oct 4;91(7):1384-90.
 

Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW, Whang EE. Retrovirally mediated RNA interference targeting the M2 subunit of ribonucleotide reductase: A novel therapeutic strategy in pancreatic cancer. Surgery. 2004 Aug;136(2):261-9.
 

Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. Ligation of EphA2 by Ephrin A1-Fc inhibits pancreatic adenocarcinoma cellular invasiveness. Biochem Biophys Res Commun. 2004 Aug 6;320(4):1096-102.
 

Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW, Whang EE. Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene. [Research Support, Non-U.S. Gov't]. 2004 Jul 29;23(34):5834-42.
 

Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity. J Am Coll Surg. 2004 Jun;198(6):953-9.
 

Duxbury MS, Ito H, Benoit E, Waseem T, Ashley SW, Whang EE. A novel role for carcinoembryonic antigen-related cell adhesion molecule 6 as a determinant of gemcitabine chemoresistance in pancreatic adenocarcinoma cells. Cancer Res. 2004 Jun 1;64(11):3987-93.
 

Ito H, Duxbury MS, Benoit E, Farivar RS, Gardner-Thorpe J, Zinner MJ, et al. Fibronectin-induced COX-2 mediates MMP-2 expression and invasiveness of rhabdomyosarcoma. Biochem Biophys Res Commun. 2004 May 28;318(2):594-600.
 

Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells. Surgery. [Research Support, Non-U.S. Gov't]. 2004 May;135(5):555-62.
 

Duxbury MS, Grikscheit TC, Gardner-Thorpe J, Rocha FG, Ito H, Perez A, et al. Lymphangiogenesis in tissue-engineered small intestine. Transplantation. 2004 Apr 27;77(8):1162-6.
 

Duxbury MS, Ito H, Ashley SW, Whang EE. CEACAM6 as a novel target for indirect type 1 immunotoxin-based therapy in pancreatic adenocarcinoma. Biochem Biophys Res Commun. 2004 May 7;317(3):837-43.
 

Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells. Clin Cancer Res. 2004 Apr 1;10(7):2307-18.
 

Duxbury MS, Ito H, Ashley SW, Whang EE. CEACAM6 cross-linking induces caveolin-1-dependent, Src-mediated focal adhesion kinase phosphorylation in BxPC3 pancreatic adenocarcinoma cells. J Biol Chem. 2004 May 28;279(22):23176-82.
 

Duxbury MS, Ito H, Ashley SW, Whang EE. c-Src-dependent cross-talk between CEACAM6 and alphavbeta3 integrin enhances pancreatic adenocarcinoma cell adhesion to extracellular matrix components. Biochem Biophys Res Commun. 2004 Apr 23;317(1):133-41.
 

Duxbury MS, Whang EE. RNA interference: a practical approach. J Surg Res. 2004 Apr;117(2):339-44.
 

Duxbury MS, Brodribb AJ. Localised megacolon complicating neurofibromatosis type 1. Dig Surg. 2004;21(2):106-7.
 

Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma. Oncogene. [Research Support, Non-U.S. Gov't]. 2004 Feb 19;23(7):1448-56.
 

Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells. Oncogene. [Research Support, Non-U.S. Gov't]. 2004 Jan 15;23(2):465-73.
 

Duxbury MS, Ashley SW, Whang EE. Inhibition of pancreatic adenocarcinoma cellular invasiveness by blebbistatin: a novel myosin II inhibitor. Biochem Biophys Res Commun. 2004 Jan 23;313(4):992-7.
 

Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene. [Comparative Study
Research Support, Non-U.S. Gov't]. 2004 Feb 26;23(8):1539-48.

 

Duxbury MS, Blake SM, Dashfield A, Lambert AW. A randomised trial of knife versus diathermy in pilonidal disease. Ann R Coll Surg Engl. 2003 Nov;85(6):405-7.
 

Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW, Whang EE. RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity. Biochem Biophys Res Commun. 2003 Nov 21;311(3):786-92.
 

Duxbury MS, Finlay IG, Butcher M, Lambert AW. Use of a vacuum assisted closure device in pilonidal disease. J Wound Care. 2003 Oct;12(9):355.
 

Duxbury MS, Waseem T, Ito H, Robinson MK, Zinner MJ, Ashley SW, et al. Ghrelin promotes pancreatic adenocarcinoma cellular proliferation and invasiveness. Biochem Biophys Res Commun. 2003 Sep 19;309(2):464-8.
 

Ramsanahie A, Duxbury MS, Grikscheit TC, Perez A, Rhoads DB, Gardner-Thorpe J, et al. Effect of GLP-2 on mucosal morphology and SGLT1 expression in tissue-engineered neointestine. Am J Physiol Gastrointest Liver Physiol. 2003 Dec;285(6):G1345-52.
 

Duxbury MS, Brodribb AJ, Oppong FC, Hosie KB. Management of colorectal cancer: variations in practice in one hospital. Eur J Surg Oncol. 2003 May;29(4):400-2.
 

Duxbury MS, Rossiter ND, Lambert AW. Cable ties for pelvic stabilisation. Ann R Coll Surg Engl. 2003 Mar;85(2):130.
 

Duxbury MS, Brown C, Lambert A. Surgical gloves. How do you change yours? Br J Perioper Nurs. 2003 Jan;13(1):17-20.
 

Duxbury MS, Wells IP, Roobottom C, Marshall A, Lambert AW. Endovascular repair of spontaneous non-aneurysmal aortocaval fistula. Eur J Vasc Endovasc Surg. 2002 Sep;24(3):276-8.

Selected book chapters

 

Cancer of the Gallbladder and bile ducts, E Whang, M Duxbury, F Rocha, M Zinner
In: Maingot’s Abdominal Operations, 12th ed. Edited by M Zinner & S Ashley

Pancreaticobiliary emergencies, MS Duxbury
In: A Companion to Specialist Surgical Practice: Core topics in General and Emergency
Surgery 5th Ed. Edited by S Paterson-Brown.

Benign solid tumors of the adult liver, MS Duxbury & OJ Garden
In: Surgical Management of Hepatobiliary and Pancreatic Disorders. Edited by G Poston, D'Angelica, Adam & Poon.

Principles of cancer management, MS Duxbury
In: Fundamentals of Surgical Practice. 3rd Ed. Edited by AN Kingsnorth & AA Majid.

Hepatobiliary & Pancreatic Surgery, MS Duxbury
In: Fundamentals of Surgical Practice. 3rd Ed. Edited by AN Kingsnorth & DM Bowley.

Principles of cancer management, MS Duxbury & AP Forrest
In: Fundamentals of Surgical Practice. 2nd Ed. Edited by AN Kingsnorth & AA Majid.

Benign liver lesions, MS Duxbury & OJ Garden
In: Surgical Management of Hepatobiliary & Pancreatic Disorders, 2nd Ed. Poston, D'Angelica, Adam & Poon.